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There is prodigious strength in sorrow and despair.

A Tale of Two Cities
Don't despair, not even over the fact that you don't despair. Just when everything seems over with, new forces come marching up, and precisely that means that you are alive. And if they don't, then everything is over with here, once and for all.

Despair is the result of each earnest attempt to go through life with virtue, justice and understanding, and to fulfill their requirements. Children live on one side of despair, the awakened on the other side.

The Journey to the East
There are circumstances in which despair does not imply inactivity
Never despair. But if you do, work on in despair
A speculative despair is unpardonable where it is our duty to act
There is no greater folly in the world than for a man to despair
Despair gives courage to a coward
Despair defies even despotism
Despair ruins some, presumption many
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On Anger: "For every minute you remain angry, you give up sixty seconds of peace of mind."
On Destiny: "Our destiny exercises its influence over us even when, as yet, we have not learned its nature: it is our future that lays down the law of our today."
Human, All Too Human
On Friendship: "A crowd is not company; and faces are but a gallery of pictures; and talk but a tinkling cymbal, where there is no love."